New Alzheimer’s Discovery Could Change How Scientists Fight the Disease

For decades, Alzheimer’s research has concentrated heavily on amyloid plaques and tau tangles, the abnormal proteins that accumulate in affected brains. A new study from ETH Zurich now points to another possible driver: a damaged form of the protein GRK2 that disrupts the energy-producing machinery inside nerve cells.

The researchers also developed an experimental treatment called Compound 10, which interrupted this damaging process in cells and mice. The results are promising, but the compound has not been tested in people and is not an approved Alzheimer’s treatment. The study was published in Cell Reports Medicine on March 26, 2026.